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Upstate Vet Emergency & Specialty Care (UV - Greenville)

Welcome to Upstate Vet

Providing exceptional veterinary specialty and emergency care for pets in Greenville, Simpsonville, Spartanburg, and the broader Upstate South Carolina, Western North Carolina, Eastern Tennessee, and Northern Georgia regions since 1978.

Give Us A Call

Hours of Operation

  • Mon

    8:00am - 2:00am

  • Tue

    8:00am - 2:00am

  • Wed

    8:00am - 2:00am

  • Thu

    8:00am - 2:00am

  • Fri

    8:00am - 2:00am

  • Sat

    8:00am - 12:00am

  • Sun

    8:00am - 12:00am

  • Our ER is operating under limited hours. For hospitalized patients, we have a team onsite providing continuous care. Our specialty service hours are Monday-Friday from 8:00am-5:30pm.

Exterior view of the Upstate Vet building

Our Commitment


At Upstate Vet, we understand that pets are members of the family. Our dedicated team of doctors and medical staff provides diagnostic, advanced medical, emergency, and specialty care in partnership with your family veterinarian, helping give your pet a complete healthcare team when they need it most.

Client Reviews & Testimonials

We value feedback from our clients. Here is just a small sample of the hundreds of happy and healthy pets that we have cared for.

★★★★★

They have an amazing staff! They are very knowledgable, compassionate and truly care about animals and their owners. Ross had to spend the night and was taken good care of during his stay. They called me with updates and provided a plan that helped him recovery quickly so he could get back to doing the things he loves. Dr. Rathke and the entire staff are wonderful! Thank you all!

Cathy G.

★★★★★

Dr. Martinez and his team went above and beyond with our German Shepherd, Ringo. We brought Ringo in February and received the devastating news of cancer. Dr. Martinez took the time to cover all our options. The treatment plan we chose put Ringo in complete remission and we were ecstatic when we got to ring the bell!

Tracy H.

★★★★★

We saw Dr. V with our dog that has chronic kidney disease. She was excellent and thoroughly explained the condition, tests done, plan and follow up. Her team is also very kind and helpful. Their care is outstanding!

Debra M.